Smith-Palmer, A and Stewart, J and Fyfe, Lorna (2002) Inhibition of listeriolypin O and phosphatidylcholine – specific phospholipase C production in Listeria monocytogeres by subinhibitory concentrations of plant essential oils. Journal of Medical Microbiology, 51 (7). pp. 567-574. ISSN 0022-2615
|PDF - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader|
Official URL: http://jmm.sgmjournals.org/content/51/7/567.long
Successful infection by Listeria monocytogenes is dependent upon a range of bacterial extracellular proteins including a cytolysin termed listeriolysin O and phosphatidylcholine-specific phospholipase C. Five plant essential oils--bay, clove, cinnamon, nutmeg and thyme--significantly reduced the production of listeriolysin O by L. monocytogenes. The greatest change was observed after culture with oil of thyme, which reduced haemolysis to 52.1 haemolytic units (HU)/ml compared with 99.8 HU/ml observed with the control. Oil of clove was the only oil that also significantly reduced phosphatidylcholine-specific phospholipase C activity. These changes were observed despite the oils causing no change to the final bacterial concentration or total extracellular protein concentration.
|Deposited On:||26 Sep 2012 13:08|
|Last Modified:||26 Sep 2012 13:08|
Repository Staff Only: item control page