Inhibition of listeriolypin O and phosphatidylcholine – specific phospholipase C production in Listeria monocytogeres by subinhibitory concentrations of plant essential oils



Smith-Palmer, A and Stewart, J and Fyfe, Lorna (2002) Inhibition of listeriolypin O and phosphatidylcholine – specific phospholipase C production in Listeria monocytogeres by subinhibitory concentrations of plant essential oils. Journal of Medical Microbiology, 51 (7). pp. 567-574. ISSN 0022-2615

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Abstract

Successful infection by Listeria monocytogenes is dependent upon a range of bacterial extracellular proteins including a cytolysin termed listeriolysin O and phosphatidylcholine-specific phospholipase C. Five plant essential oils--bay, clove, cinnamon, nutmeg and thyme--significantly reduced the production of listeriolysin O by L. monocytogenes. The greatest change was observed after culture with oil of thyme, which reduced haemolysis to 52.1 haemolytic units (HU)/ml compared with 99.8 HU/ml observed with the control. Oil of clove was the only oil that also significantly reduced phosphatidylcholine-specific phospholipase C activity. These changes were observed despite the oils causing no change to the final bacterial concentration or total extracellular protein concentration.

Item Type: Article
Divisions: School of Health Sciences > Dietetics, Nutrition and Biological Sciences
Date Deposited: 26 Sep 2012 12:08
Last Modified: 19 Mar 2014 13:00
URI: http://eresearch.qmu.ac.uk/id/eprint/2932

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