Effects of exercise training on aerobic and functional capacity of end-stage renal disease patients



Koufaki, Pelagia and Mercer, Tom and Naish, P F (2002) Effects of exercise training on aerobic and functional capacity of end-stage renal disease patients. Clinical Physiology and Functional Imaging, 22 (2). pp. 115-124. ISSN 1475-0961

Full text not available from this repository.

Abstract

The aim was to assess the effects of exercise training on aerobic and functional capacity of patients with end-stage renal disease (ESRD). Patients completed an incremental exercise test on a cycle ergometer to determine VO2 peak and VO2 at ventilatory threshold (VT; V-slope). On a separate day they performed two constant load exercise tests on a cycle ergometer at 90% of VT and at a workload of 33 W, to determine VO2 kinetics. Functional capacity was assessed using measurements of sit-to-stands (STS-5, STS-60) and a walk test. Dialysis patients were randomly allocated to an exercise (ET: n=18, age=57·3 years) or control (C: n=15, age=50·5 years) group. The ET group participated in an exercise training programme involving cycling for 3 months. Repeated measures ANOVA revealed significant time by group interactions (P < 0·05) following training for VO2 peak (ET: 17 ± 6·1 versus 19·9 ± 6·3, C: 19·5 ± 4·7 versus 18·8 ± 4·9 ml kg min–1) and VO2–VT (ET: 10·7 ± 3·5 versus 11·8 ± 3·3, C:12·9 ± 3·2 versus 11·9 ± 3·5 ml kg min–1). VO2 kinetics remained unchanged in both groups at 90% -VT, but a trend (P=0·059) towards faster kinetics at the 33 W was observed (ET: 49·6 ± 19·5 versus 37·8 ± 12·7, C: 42·8 ± 13 versus 49·4 ± 20·2 s). Significant time by group interactions (P < 0·05) were also observed for STS-5 (ET: 14·7 ± 6·2 versus 11·0 ± 3·3, C: 12·8 ± 4·4 versus 12·7 ± 4·8 s) and STS-60 measurements (ET: 21·2 ± 7·2 versus 26·9 ± 6·2, C: 23·7 ± 6·8 versus 24·1 ± 7·2). Three months of exercise rehabilitation significantly improves peak exercise capacity of patients with ESRD. Measurements of VO2 kinetics and functional capacity suggest that longer time might be needed to induce peripheral adaptations.

Item Type: Article
Uncontrolled Keywords: renal failure • rehabilitation • VO2 kinetics • VO2 peak
Divisions: School of Health Sciences > Physiotherapy
Date Deposited: 10 Dec 2009 15:31
Last Modified: 13 Feb 2014 10:51
URI: http://eresearch.qmu.ac.uk/id/eprint/994

Actions (login required)

View Item View Item