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dc.rights.licenseCreative Commons Attribution 4.0 License
dc.contributor.authorGeneen, Louise J.
dc.contributor.authorKinsella, Jodie
dc.contributor.authorZanotto, Tobia
dc.contributor.authorNaish, Patrick F.
dc.contributor.authorMercer, Tom
dc.date.accessioned2021-04-08T12:22:58Z
dc.date.available2021-04-08T12:22:58Z
dc.date.issued2021-03-30
dc.identifierhttps://eresearch.qmu.ac.uk/bitstream/handle/20.500.12289/11210/11210.pdf
dc.identifier.citationGeneen, L. J., Kinsella, J., Zanotto, T., Naish, P. F. & Mercer, T. H. (2021) 'Validity and reliability of high-resolution ultrasound imaging for the assessment of regional body composition in stage 5 chronic kidney disease patients undergoing continuous ambulatory peritoneal dialysis', Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 42(1), pp. 57-64.
dc.identifier.issn0896-8608
dc.identifier.issn1718-4304
dc.identifier.urihttps://eresearch.qmu.ac.uk/handle/20.500.12289/11210
dc.identifier.urihttps://doi.org/10.1177/08968608211002384
dc.descriptionTom Mercer - ORCID: 0000-0002-5078-4769 https://orcid.org/0000-0002-5078-4769
dc.descriptionTobia Zanotto - ORCID 0000-0002-6571-4763 https://orcid.org/0000-0002-6571-4763
dc.description.abstractBackground: Accurate measurement of muscle mass is an important research and clinical tool. High-resolution ultrasound (US) has shown potential as a method to assess muscle and fat mass at specific anatomical sites. However, there is limited evidence for the reliability of US to measure muscle size in patients receiving continuous ambulatory peritoneal dialysis (CAPD). Therefore, we examined the validity and reliability of an US method compared to a gold standard comparison for the assessment of a quadriceps muscle in this clinical population. Methods: Twenty people receiving CAPD (mean age = 56.5 ± 16.7 years) at a single dialysis unit were assessed on two occasions, 7 days apart. Measures of the mid-thigh, such as vastus lateralis (VL) anatomical cross-sectional area (ACSA), VL muscle thickness and subcutaneous fat thickness were compared for US reliability and validity compared to magnetic resonance imaging (MRI) measures. Results: US had high validity against gold standard MRI measures, with intraclass correlation coefficients (ICC) equating to VL ACSA of 0.95, VL thickness of 0.99 and fat thickness of 0.98. The US measurements also exhibited high intra-rater reliability (ICCs: VL thickness = 0.98, total muscle thickness = 0.97 and fat thickness = 0.99) in measuring body composition at the mid-VL site in the study population. Conclusions: Valid assessment of regional body composition can be achieved via high-resolution US in patients receiving CAPD. The validity and reliability of the US in repeated measures (in comparison to the gold standard MRI) warrant further investigation in the wider chronic kidney disease population.
dc.format.extent57-64
dc.publisherSAGE
dc.relation.ispartofPeritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
dc.rights© The Author(s) 2021
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectNephrology
dc.subjectGeneral Medicine
dc.titleValidity and reliability of high-resolution ultrasound imaging for the assessment of regional body composition in stage 5 chronic kidney disease patients undergoing continuous ambulatory peritoneal dialysis
dc.typeArticle
dc.date.updated2021-04-08T00:49:54Z
dc.description.volume42
dc.description.ispublishedpub
refterms.dateFCD2021-04-08
qmu.authorGeneen, Louise J.
qmu.authorZanotto, Tobia
qmu.authorMercer, Tom
qmu.centreCentre for Health, Activity and Rehabilitation Research
dc.description.statuspub
dc.description.number1
refterms.dateDeposit2021-04-08


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Creative Commons Attribution 4.0 License
Except where otherwise noted, this item's license is described as Creative Commons Attribution 4.0 License