Show simple item record

dc.rights.licenseCreative Commons Attribution License CC-BY 4.0
dc.contributor.authorMitrani, Leilaen
dc.contributor.authorDickson-Hall, Lindyen
dc.contributor.authorLe Roux, Sachaen
dc.contributor.authorGrant, Alison D.en
dc.contributor.authorKielmann, Karinaen
dc.contributor.authorMlisana, Kolekaen
dc.contributor.authorMoshabela, Mosaen
dc.contributor.authorNicol, Mark P.en
dc.contributor.authorBlack, Johnen
dc.contributor.authorCox, Helenen
dc.date.accessioned2021-04-14T12:25:39Z
dc.date.available2021-04-14T12:25:39Z
dc.date.issued2021-09-21
dc.identifierhttp://eresearch.qmu.ac.uk/bitstream/handle/20.500.12289/11214/11214.pdf
dc.identifier.citationMitrani, L., Dickson-Hall, L., Le Roux, S., Grant, A. D., Kielmann, K., Mlisana, K., Moshabela, M., Nicol, M. P., Black, J. & Cox, H. (2021) Diverse clinical and social circumstances: Developing patient-centred care for DR-TB patients in South Africa. Public Health Action, 11(3), pp. 120-125.en
dc.identifier.issn2220-8372en
dc.identifier.urihttps://doi.org/10.5588/pha.20.0083
dc.identifier.urihttps://eresearch.qmu.ac.uk/handle/20.500.12289/11214
dc.descriptionKarina Kielmann - ORCID: 0000-0001-5519-1658 https://orcid.org/0000-0001-5519-1658en
dc.descriptionReplaced AM with VoR 2021-09-22.
dc.description.abstractObjective: To describe the medical, socio-economic and geographical profiles of patients with rifampicin-resistant TB (RR-TB) and the implications for the provision of patient-centred care.en
dc.description.abstractSetting 13 districts across three South African provinces.
dc.description.abstractDesign This descriptive study examined laboratory and healthcare facility records of 194 patients diagnosed with RR-TB in the third quarter of 2016.
dc.description.abstractResults Median age was 35; 120/194 (62%) of patients were male. Previous TB treatment was documented in 122/194 (63%) patients and 56/194 (29%) had a record of fluoroquinolone and/or second line injectable resistance. Of 134 (69 %) HIV positive patients, viral loads were available for 68/134 (51%) (36/68 [53%] had viral loads of >1000 copies/ml) and CD4 counts were available for 92/134 (69%) (20/92 [22%] had CD4 < 50 cells/mm3). Patients presented with varying other comorbidities including hypertension (13/194, 7%) and mental health conditions (11/194, 6%). 44/194 (23%) patients were reported to be employed. Other socio-economic challenges included substance abuse (17/194, 9%) and ill family members (17/194, 9%). 13% and 42% of patients were estimated to travel more than 20 km to reach their diagnosing and treatment-initiating healthcare facility, respectively.
dc.description.abstractConclusions. DR-TB patients had diverse medical and social challenges highlighting the need for integrated, differentiated, and patient-centred healthcare to better address specific needs and underlying vulnerabilities of individual patients.
dc.description.sponsorshipThis study was funded a Health Systems Research Initiative award from the Medical Research Council of the United Kingdom and the Wellcome Trust (MR/N015924/1). This UK funded award is part of the EDCTP2 program supported by the European Union. HC is supported by a Wellcome Trust Fellowship.en
dc.description.urihttps://doi.org/10.5588/pha.20.0083en
dc.format.extent120-125
dc.language.isoenen
dc.publisherThe Unionen
dc.relation.ispartofPublic Health Actionen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectPatient Complexityen
dc.subjectHealth Systemsen
dc.subjectIntegrated Careen
dc.titleDiverse clinical and social circumstances: Developing patient-centred care for DR-TB patients in South Africaen
dc.typeArticleen
dcterms.accessRightspublic
dcterms.dateAccepted2021-04-12
dc.date.updated2021-09-22
dc.description.volume11
dc.description.ispublishedpub
rioxxterms.typeJournal Article/Reviewen
rioxxterms.publicationdate2021-09-21
refterms.dateFCD2021-04-14
refterms.depositExceptionpublishedGoldOAen
refterms.accessExceptionNAen
refterms.technicalExceptionNAen
refterms.panelUnspecifieden
qmu.authorKielmann, Karinaen
dc.description.statuspub
dc.description.number3
refterms.versionVoRen
refterms.dateDeposit2021-04-14


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Creative Commons Attribution License CC-BY 4.0
Except where otherwise noted, this item's license is described as Creative Commons Attribution License CC-BY 4.0