Show simple item record

dc.contributor.authorKennedy, H.
dc.contributor.authorAl-Dujaili, Emad A. S.
dc.contributor.authorEdwards, C.
dc.contributor.authorTruelove, S. C.
dc.date.accessioned2018-06-29T21:33:32Z
dc.date.available2018-06-29T21:33:32Z
dc.date.issued1983-08
dc.identifierER1186
dc.identifier.citationKennedy, H., Al-Dujaili, E., Edwards, C. & Truelove, S. (1983) Water and electrolyte balance in subjects with a permanent ileostomy., Gut, vol. 24, , pp. 702-705,
dc.identifier.issn0017-5749
dc.identifier.urihttp://dx.doi.org/10.1136/gut.24.8.702
dc.identifier.urihttps://eresearch.qmu.ac.uk/handle/20.500.12289/1186
dc.description.abstractWater and electrolyte balance has been studied in 39 patients with a permanent ileostomy, who had had a proctocolectomy for ulcerative colitis. The findings have been compared with those in 39 healthy subjects who were matched for age and sex. The ileostomists were found to lose excessive quantities of water and sodium in the ileostomy effluent compared with the corresponding losses in normal faeces. The mean plasma total protein and albumin concentrations were increased in the ileostomists suggesting a state of chronic dehydration. The daily urinary output of sodium was low and the output of potassium was high. The urinary pH was low. The ileostomists had raised mean concentration of aldosterone in the plasma (p less than 0.001) and it is suggested that this is responsible for the body's partial compensation for the depletion of sodium and water, including the so-called ileostomy adaptation.
dc.format.extent702-705
dc.publisherBMJ Publishing Group Ltd
dc.relation.ispartofGut
dc.titleWater and electrolyte balance in subjects with a permanent ileostomy.
dc.typearticle
dcterms.accessRightspublic
dc.description.facultysch_die
dc.description.referencetext1 Gallagher ND, Harrison DD, Skyring AP. Fluid and electrolyte disturbances in patients with long-term established ileostomies. Gut 1962; 3: 219-23. 2 Clarke AM, Chirnside A, Hill GL, Pope G. Chronic dehydration and sodium depletion with established ileostomies. Lancet 1967; 2: 740-3. 3 Hill GL, Goligher JC, Smith AH, Mair WSJ. Longterm changes in total body water, total exchangeable sodium and total body potassium before and after ileostomy. Br J Surg 1975; 62: 524-7. 4 Turnberg LA, Morris AI, Hawker PC, Herman KJ, Shields RA, Horth CE. Intracellular electrolyte depletion in patients with ileostomies. Gut 1978; 19: 563-8. 5 Isaacs PET, Horth CE, Turnberg LA. The electrical potential difference across human ileostomy mucosa. Gastroenterdlogy 1976; 70: 52-8. 6 Harrison EM, Gallon S. Venous blood as an alternative to arterial blood for the measurement of carbon dioxide tensions. Br J Anaesth 1965; 37: 13-8. 7 Forster HV, Dempsey JA, Thomson J, Vidrak E, Dopico GA. Estimation of arterial P02, PC02, pH and lactate from arterialised venous blood. J Appl Phys 1972; 32: 134-7. 8 France CJ, Eger EI, Bendixen HH. The use of peripheral venous blood for pH and carbon dioxide tension determinations during general anesthesia. Anesthesiology 1974; 40: 311-4. 9 Stockigt JR, Collins RD, Biglierri EG. Determination of plasma renin concentration by angiotensin-1 immunoassay. Circ Res 1971; 28: suppl 11: 175-91. 10 AI-Dujaili EAS, Edwards CRW. The development and application of a direct radioimmunoassay for plasma aldosterone using 125 I-labelled ligand-comparison of three methods. J Clin Endocrinol Metab 1978; 46: 105-13. 1 lPaul AA, Southgate DAT, eds. McCance and Widdowson's The composition of foods, 4th ed. London: HMSO, 1978. 12 Wrong OM. The role of the human colon in homeostasis. In: The scientific basis of medicine annual reviews. London: Athlone Press, 1971: 195. 13 Crawford N, Brooke BN. Ileostomy chemistry. Lancet 1957; 1: 864-7. 14 Smiddy FH, Gregory SD, Smith IB, Goligher JC. Faecal loss of fluid, electrolytes and nitrogen in colitis before and after ileostomy. Lancet 1960; 1: 14-9. 15 Nuguid TP, Bacon HE, Boutwell J. An investigation of the volume of output and chemical content of ileal discharges following total colectomy and ileostomy. Surg Gynecol Obstet 1961; 113: 733-42. 16 Kramer P, Kearney MM, Ingelfinger FJ. The effect of specific foods and water loading on the ileal excreta of ileostomized human subjects. Gastroenterology 1962; 42: 535-46. 17 Kanaghinis T, Lubran M, Coghill NF. The composition of ileostomy fluid. Gut 1963; 4: 322-38. 18 King RFGJ, Millward S, Hill GL. Chemistry of ileal fluid in well-functioning ileostomies. (Abstract.) Gut 1978; 19: A456. 19 Kennedy HJ, Lee ECG, Claridge G, Truelove SC. The health of subjects living with a permanent ileostomy. Q J Med 1982; 51: 341-57. 20 Clarke AM, McKenzie RG. Ileostomy and the risk of urinary uric acid stones. Lancet 1961; 2: 395-7. 21 Singer AM, Bennett RC, Carter NG, Hughes ESR. Blood and urinary changes in patients with ileostomies and ileorectal anastomoses. Br Med J 1973; 3: 141-3. 22 Hill JR, Mair WSJ, Goligher JC. Impairment of ileostomy adaptation in patients after ileal resection. Gut 1974; 15: 982-7. 23 Phillips SF, Giller J. The contribution of the colon to electrolyte and water conservation in man. J Lab Clin Med 1973; 81: 733-46. 24 Debongnie JC, Phillips SF. Capacity of the human colon to absorb fluid. Gastroenterology 1978; 74: 698-703. 25 MacGregor IL, Wiley ZD, Sleisenger MH. The role of bile acids;in determining ileal flow rates in normal subjects following ileostomy. Digestion 1978; 18: 192- 200. 26 LeVeen HH, Lyons A, Becker E. Physiological adaptation to ileostomy. Am J Surg 1962; 103: 35-43. 27 Hill GL, Mair WSJ, Edwards JP, Goligher JC. Decreased trypsin and bile acids in ileal fistula drainage during the administration of a chemically defined liquid elemental diet. Br J Surg 1976; 63: 133-6. 28 Wrong OM. Disorders of the gastro-intestinal tract. In: Thompson RHS, Wootton IDP, eds. Biochemical disorders in human disease. London: Churchill, 1970: 661-88.
dc.description.volume24
dc.identifier.doihttp://doi:10.1136/gut.24.8.702
dc.description.ispublishedpub
dc.description.eprintid1186
rioxxterms.typearticle
qmu.authorAl-Dujaili, Emad A. S.
dc.description.statuspub
dc.description.number8


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record