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dc.contributor.authorAlmoosawi, Suzana
dc.contributor.authorMcDougall, G. J.
dc.contributor.authorFyfe, Lorna
dc.contributor.authorAl-Dujaili, Emad A. S.
dc.date.accessioned2018-06-29T21:33:11Z
dc.date.available2018-06-29T21:33:11Z
dc.date.issued2010-08-20
dc.identifierER1832
dc.identifier.citationAlmoosawi, S., McDougall, G., Fyfe, L. & Al-Dujaili, E. (2010) Investigating the inhibitory activity of green coffee and cacao bean extracts on pancreatic lipase. Nutrition Bulletin, 35(3), pp. 207-212.
dc.identifier.issn1471-9827
dc.identifier.urihttps://doi.org/10.1111/j.1467-3010.2010.01841.x
dc.identifier.urihttps://eresearch.qmu.ac.uk/handle/20.500.12289/1832
dc.description.abstractThe present study investigated the effects of green coffee bean extract and Theobroma cacao bean extract on pancreatic lipase activity in vitro. Green coffee bean extract produced a J-shaped dose-dependent inhibition of pancreatic lipase with the percentage inhibition of pancreatic lipase ranging from 11.8% to 61.5%. Similar concentrations of Theobroma cacao failed to produce any effect on pancreatic lipase. Non-linear regression analysis revealed that the concentration of green coffee bean extract required to elicit a 50% inhibition of pancreatic lipase activity (IC50) was approximately 43 _M. In conclusion, extracts of green coffee beans but not Theobroma cacao possess potent inhibitory activity against pancreatic lipase. 2010 The Authors. Journal compilation 2010 British Nutrition Foundation.
dc.format.extent207-212
dc.publisherWiley Interscience
dc.relation.ispartofNutrition Bulletin
dc.titleInvestigating the inhibitory activity of green coffee and cacao bean extracts on pancreatic lipase
dc.typearticle
dcterms.accessRightsrestricted
dc.description.facultysch_die
dc.description.volume35
dc.description.ispublishedpub
dc.description.eprintid1832
rioxxterms.typearticle
qmu.authorAl-Dujaili, Emad A. S.
qmu.authorAlmoosawi, Suzana
qmu.authorFyfe, Lorna
dc.description.statuspub
dc.description.number3


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