Now showing items 1-16 of 16

    • Awareness of and support for speech, language and communication needs in Children’s Hearings 

      Clark, Ann; Fitzsimons, Dermot (CELCIS (Centre for Excellence for Looked After Children in Scotland), 2018-12-18)
      Looked-after children commonly experience speech, language and communication needs (SLCN) (McCool & Stevens, 2011; Department for Education, 2017). Unidentified and unmet SLCN have negative effects on children’s educational ...
    • Unidentified and Unmet: Hidden speech, language and communication needs of looked-after children and young people in Scotland 

      Clark, Ann; Fitzsimons, Dermot (Royal College of Speech and Language Therapists, 2016-05)
    • Reply to Pembrey et al: 'ZNF277 microdeletions, specific language impairment and the meiotic mismatch methylation (3M) hypothesis' 

      Ceroni, Fabiola; Simpson, Nuala H.; Francks, Clyde; Baird, Gillian; Conti-Ramsden, Gina; Clark, Ann; Bolton, Patrick F.; Hennessy, Elizabeth R.; Donnelly, Peter; Bentley, David R.; Martin, Hilary; Parr, Jeremy; Pagnamenta, Alistair T.; Maestrini, Elena; Bacchelli, Elena; Fisher, Simon E.; Newbury, Dianne F. (2015-09)
    • Lack of replication for the myosin-18B association with mathematical ability in independent cohorts 

      Pettigrew, K. A.; Fajutrao Valles, S.; Moll, K.; Northstone, K.; Ring, S.; Pennell, C.; Wang, C.; Leavett, R.; Hayiou-Thomas, M. E.; Thompson, P.; Simpson, N. H.; Fisher, S. E.; Whitehouse, A. J. O.; Snowling, M. J.; Newbury, D. F.; Paracchini, S.; Clark, Ann; Watson, Jocelynne (2015-04-01)
      Twin studies indicate that dyscalculia (or mathematical disability) is caused partly by a genetic component, which is yet to be understood at the molecular level. Recently, a coding variant (rs133885) in the myosin-18B ...
    • Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia. 

      Simpson, Nuala H.; Addis, Laura; Brandler, William M.; Slonims, Vicky; Clark, Ann; Watson, Jocelynne; Scerri, Thomas S.; Hennessy, Elizabeth R.; Bolton, Patrick F.; Conti-Ramsden, Gina; Fairfax, Benjamin P.; Knight, Julian C.; Stein, John; Talcott, Joel B.; O'Hare, Anne; Baird, Gillian; Paracchini, Silvia; Fisher, Simon E.; Newbury, Dianne F.; Consortium, Sli (Wiley, 2014-04)
      AIM Sex chromosome aneuploidies increase the risk of spoken or written language disorders but individuals with specific language impairment (SLI) or dyslexia do not routinely undergo cytogenetic analysis. We assess the ...
    • Homozygous microdeletion of exon 5 in ZNF277 in a girl with specific language impairment. 

      Ceroni, Fabiola; Simpson, Nuala H.; Francks, Clyde; Baird, Gillian; Conti-Ramsden, Gina; Clark, Ann; Bolton, Patrick F.; Hennessy, Elizabeth R.; Donnelly, Peter; Bentley, David R.; Martin, Hilary; Parr, Jeremy; Pagnamenta, Alistair T.; Maestrini, Elena; Bacchelli, Elena; Fisher, Simon E.; Newbury, Dianne F. (Nature Publishing Group, 2014-02)
      Specific language impairment (SLI), an unexpected failure to develop appropriate language skills despite adequate non-verbal intelligence, is a heterogeneous multifactorial disorder with a complex genetic basis. We identified ...
    • Tangled terminology: what's in a name? 

      Clark, Ann; Allstaff, Linda; Carter, Glenn; Chalmers, Cara; Ross, Eilidh; Simpson, Sarah (RCSLT, 2013-09)
      Ann Clark and colleagues from the SLI in Scotland SIG Committee look at the use of terminology to describe the needs of children they support
    • Revisiting the phonological deficit in dyslexia: are implicit non-orthographic representations impaired? 

      Dickie, Catherine; Ota, Mitsuhiko; Clark, Ann (Cambridge University Press, 2013-07)
      This study investigates whether developmental dyslexia involves an impairment in implicit phonological representations, as distinct from orthographic representations and metaphonological skills. A group of adults with ...
    • Unmet need in Scotland's criminal justice system 

      Clark, Ann; Barrow, Ellie; Hartley, Kim (RCSLT, 2012-02)
      Research shows that around 60% of young people in contact with youth justice services have speech, language and communication needs. This article reports on the most comprehensive survey of speech and language therapy in ...
    • CMIP and ATP2C2 Modulate Phonological Short-Term Memory in Language Impairment 

      Newbury, D. F.; Winchester, Laura; Addis, L.; Paracchini, Silvia; Buckingham, Lyn-Louise; Clark, Ann; Cohen, W.; Cowie, H.; Dworzynski, Katharina; Everitt, Andrea; Goodyer, I. M.; Hennessy, E.; Kindley, A. D.; Miller, Laura L.; Nasir, J.; O'Hare, Anne; Shaw, D.; Simkin, Z.; Simonoff, E.; Slonims, V.; Watson, Jocelynne; Ragoussis, Jiannis; Fisher, S. E.; Seckl, J.; Helms, P. J.; Bolton, P. F.; Pickles, A.; Conti-Ramsden, G.; Baird, G.; Bishop, DVM; Monaco, A. P. (2009-08-14)
      Specific language impairment (SLI) is a common developmental disorder characterized by difficulties in language acquisition despite otherwise normal development and in the absence of any obvious explanatory factors. We ...
    • Genetic and phenotypic effects of phonological short-term memory and grammatical morphology in specific language impairment 

      Falcaro, M.; Pickles, A.; Newbury, D. F.; Addis, L.; Banfield, E.; Fisher, S. E.; Monaco, A. P.; Simkin, Z.; Conti-Ramsden, G.; Newbury, D. F.; Banfield, E.; Addis, L.; Cleak, J. D.; Cardon, L. R.; Merriden, M. J.; Goodyer, I. M.; Simonoff, E.; Bolton, P. F.; Slonims, V.; Baird, G.; Everitt, Andrea; Hennessy, E.; Shaw, D.; Helms, P. J.; Kindley, A. D.; Clark, Ann; Watson, Jocelynne; O'Hare, Anne; Seckl, J.; Cowie, H.; Cohen, W.; Nasir, J.; Bishop, DVM (2008-06)
      Deficits in phonological short-term memory and aspects of verb grammar morphology have been proposed as phenotypic markers of specific language impairment (SLI) with the suggestion that these traits are likely to be under ...
    • The phonological deficit in developmental dyslexia : is there a suprasegmental component? 

      Dickie, Catherine; Ota, Mitsuhiko; Clark, Ann (2007-08)
      Adult dyslexics were tested on a range of tasks which were presented in two closely matched versions: a segmental version and a suprasegmental version. The tasks targeted phonological contrasts on one hand and the metalinguistic ...
    • Receptive language disorder in childhood: Familial aspects and long term outcomes: Results from a Scottish study 

      Clark, Ann; O'Hare, Anne; Watson, Jocelynne; Cohen, W.; Cowie, H.; Elton, R.; Nasir, J.; Seckl, J. (2007)
      Background and aims: Little is known about the familial characteristics of children with severe receptive specific language impairment (SLI). Affected children are more likely to have long-term problems than those with ...
    • Multivariate Linkage Analysis of Specific Language Impairment (SLI) 

      Monaco, A. P.; Watson, Jocelynne; Clark, Ann (2007)
      Specific language impairment (SLI) is defined as an inability to develop appropriate language skills without explanatory medical conditions, low intelligence or lack of opportunity. Previously, a genome scan of 98 families ...
    • Highly Significant Linkage to the SLI1 Locus in an Expanded Sample of Individuals Affected by Specific Language Impairment 

      Watson, Jocelynne; Clark, Ann (2004)
      Specific language impairment (SLI) is defined as an unexplained failure to acquire normal language skills despite adequate intelligence and opportunity. We have reported elsewhere a full-genome scan in 98 nuclear families ...
    • Speech and language functioning in paediatric HIV disease. 

      Clark, Ann; Dean, E.; Mok, J. (Taylor & Francis Ltd, 2001)
      The Human Immunodeficiency Virus (HIV) can potentially cause impairment to linguistic functioning. This study was the first to compare selected aspects of speech motor control, expressive language and receptive language ...