The effects of exercise training on muscle with special reference to patients with CKD

Abstract

We've known for many years now that muscle wasting and reduced functional capacity are hallmark characteristics of CKD.However, we now know, because of the advantages with molecular biology, that this is an over simplistic characterization of the relationship between synthesis and degradation and there's considerable cross-talk between these areas. Regardless though, whether it be due to increased degradation or reduced synthesis, the end outcome of muscle wasting leads to very, very poor outcome