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    Performance of the Hospital Anxiety and Depression Scale as a screening tool for major depressive disorder in cancer patients

    Date
    2007-07
    Author
    Walker, J.
    Postma, Kirstine
    McHugh, Gillian S.
    Rush, Robert
    Coyle, Brian
    Strong, V.
    Sharpe, Michael
    Metadata
    Show full item record
    Citation
    Walker, J., Postma, K., McHugh, G., Rush, R., Coyle, B., Strong, V. & Sharpe, M. (2007) Performance of the Hospital Anxiety and Depression Scale as a screening tool for major depressive disorder in cancer patients, Journal of Psychosomatic Research, vol. 63, , pp. 83-91,
    Abstract
    Objectives (1) To assess the overall performance of the Hospital Anxiety and Depression Scale (HADS) as a screening instrument to identify cases of major depressive disorder (MDD) in mixed cancer outpatients. (2) To determine the sensitivity and specificity of various HADS cut-off scores. (3) To recommend an optimal HADS cut-off score for use in this population. Methods A cross-sectional questionnaire and interview survey of consecutive patients attending outpatient clinics in a regional cancer centre in Edinburgh, Scotland, United Kingdom. Results Thirty (8.3%) of 361 patients met criteria for MDD at interview. With the use of the total HADS score to identify these cases of MDD, the area under the receiver operating characteristic curve was 0.94 (95% CI, 0.91–0.97). A cut-off of 14/15 gave a sensitivity of 0.87 (95% CI, 0.70–0.95), a specificity of 0.85 (95% CI, 0.81–0.89), and a positive predictive value of 0.35, and was considered optimal. Conclusion The HADS can be used effectively as an initial screening tool for the detection of MDD in outpatients attending mixed cancer clinics
    URI
    https://eresearch.qmu.ac.uk/handle/20.500.12289/438
    Official URL
    http://dx.doi.org/10.1016/j.jpsychores.2007.01.009
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    • Psychology, Sociology and Education

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