Physiotherapy Rehabilitation for People With Progressive Multiple Sclerosis: A Systematic Review
Coulter, Elaine H.
Mattison, P. G. G.
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Campbell, E., Coulter, E., Mattison, P., Miller, L., McFadyen, A. & Paul, L. (2015) Physiotherapy Rehabilitation for People With Progressive Multiple Sclerosis: A Systematic Review, Archives of Physical Medicine and Rehabilitation, vol. 97, , pp. 141-151.e3,
Objective: To assess the efficacy of physiotherapy interventions, including exercise therapy, for the rehabilitation of people with progressive multiple sclerosis. Data Sources: Five databases (Cochrane Library, Physiotherapy Evidence Database [PEDro], Web of Science Core Collections, MEDLINE, Embase) and reference lists of relevant articles were searched. Study Selection: Randomized experimental trials, including participants with progressive multiple sclerosis and investigating a physiotherapy intervention or an intervention containing a physiotherapy element, were included. Data Extraction: Data were independently extracted using a standardized form, and methodologic quality was assessed using the PEDro scale. Data Synthesis: Thirteen studies (described by 15 articles) were identified and scored between 5 and 9 out of 10 on the PEDro scale. Eight interventions were assessed: exercise therapy, multidisciplinary rehabilitation, functional electrical stimulation, botulinum toxin type A injections and manual stretches, inspiratory muscle training, therapeutic standing, acupuncture, and body weightesupported treadmill training. All studies, apart from 1, produced positive results in at least 1 outcome measure; however, only 1 article used a power calculation to determine the sample size and because of dropouts the results were subsequently underpowered.