Show simple item record

dc.rights.licenseCreative Commons Attribution licence
dc.contributor.authorStockton, Angela
dc.contributor.authorFarhat, Grace
dc.contributor.authorMcDougall, Gordon J.
dc.contributor.authorAl-Dujaili, E. A. S.
dc.date.accessioned2018-06-29T21:32:51Z
dc.date.available2018-06-29T21:32:51Z
dc.date.issued2017-08-09
dc.identifierER4973
dc.identifier.citationStockton, A., Farhat, G., McDougall, G. & Al-Dujaili, E. (2017) Effect of pomegranate extract on blood pressure and anthropometry in adults: a double-blind placebo-controlled randomised clinical trial, Journal of Nutritional Science, 6, e39.
dc.identifier.issn2048-6790
dc.identifier.urihttps://doi.org/10.1017/jns.2017.36
dc.identifier.urihttps://eresearch.qmu.ac.uk/handle/20.500.12289/4973
dc.description.abstractPomegranate (Punica granatum), a polyphenol-rich fruit, has been suggested to reduce cardiovascular risk due to its antioxidant properties. Hypertension and obesity are the most preventable cardiovascular risk factors. Few studies on blood pressure and/or body-weight status have been conducted in human subjects. Previous investigations have tended to focus on pomegranate juice. The aim of the present study was to investigate the effect of pomegranate extract (PE) on blood pressure and anthropometric measures in adults with no symptomatic disease. A total of fifty-five participants enrolled in a randomised double-blinded placebo-controlled clinical trial where they were assigned to either PE capsules or placebo capsules for 8 weeks. Blood pressure, body weight, waist circumference, waist:hip ratio (WHR) and body composition (lean body mass, body fat) were measured at baseline, week 4 and week 8. Results showed a significant decrease in diastolic blood pressure after 8 weeks (by 279 (sd 532) mmHg; P < 005), while the decrease in systolic blood pressure did not reach statistical significance (257 (sd 74) mmHg; P > 005). Body fat percentage, lean body mass, waist circumference and WHR did not significantly differ between groups at the end of the intervention. Results suggest that PE may reduce blood pressure and possibly prevent hypertension in the normotensive population. Further large trials are required to elucidate this effect.
dc.format.extente39
dc.publisherCUP
dc.relation.ispartofJournal of Nutritional Science
dc.rightsCopyright The Author(s) 2017
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleEffect of pomegranate extract on blood pressure and anthropometry in adults: a double-blind placebo-controlled randomised clinical trial
dc.typearticle
dcterms.accessRightspublic
dc.description.facultysch_die
dc.description.volume6
dc.identifier.doihttp://doi:10.1017/jns.2017.36
dc.description.ispublishedpub
dc.description.eprintid4973
rioxxterms.typearticle
refterms.dateAccepted2017-06-16
refterms.dateFCA2017-10-24
refterms.dateFCD2017-10-24
qmu.authorFarhat, Grace
qmu.authorStockton, Angela
dc.description.statuspub


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Creative Commons Attribution licence
Except where otherwise noted, this item's license is described as Creative Commons Attribution licence