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dc.contributor.authorSiddiqui, Muhammad A.
dc.contributor.authorAshraff, Suhel
dc.contributor.authorSantos, Derek
dc.contributor.authorRush, Robert
dc.contributor.authorCarline, Tom
dc.contributor.authorRaza, Zahid
dc.date.accessioned2018-06-29T21:48:50Z
dc.date.available2018-06-29T21:48:50Z
dc.date.issued2018-03-07
dc.identifierER5237
dc.identifier.citationSiddiqui, M., Ashraff, S., Santos, D., Rush, R., Carline, T. & Raza, Z. (2018) Development of prognostic model for fistula maturation in patients with advanced renal failure, Renal Replacement Therapy, vol. 4, , ,
dc.identifier.issn2059-1381
dc.identifier.urihttps://doi.org/10.1186/s41100-018-0153-z
dc.identifier.urihttps://eresearch.qmu.ac.uk/handle/20.500.12289/5237
dc.description.abstractBackground: This study aimed to explore the role of patient's characteristic and haematological factors as predictive on the maturation of arteriovenous fistulae in patients who underwent vascular access surgery at the Royal Infirmary of Edinburgh. Methods: Retrospective data from 300 patients who had undergone fistula creation between February 2007 and October 2010 was examined. A predictive logistic regression model was developed using the backward stepwise procedure. Model performance, discrimination and calibration, was assessed using the receiver operating characteristics (ROC) curve and Hosmer and Lemeshow goodness of fit test. Results: Three variables were identified which independently influenced fistula maturation. Males were twice as likely to undergo fistula maturation, compared to that of females (odds ratio (OR) 0.514; 95% confidence interval (CI) 0.308-0.857), patients with no evidence of peripheral vascular disease (PVD) were three times more likely to mature their fistula (OR 3.140; 95% CI 1.596-6.177) and a pre-operative vein diameter > 2.5 mm resulted in a fivefold increase in fistula maturation compared to a vein size less than 2.5 mm (OR 4.532; 95% CI 2.063-9.958). The model for fistula maturation had fair discrimination as indicated by the area under the ROC curve (0.68; 95% CI 0.615-0. 738) but good calibration indicated by Hosmer and Lemeshow test (p = 0.79). Conclusion: Gender, PVD and vein size are independent predictors of arteriovenous fistula maturation. The clinical utility of these risk equation in the maturation of arteriovenous fistulae requires further validation in the newly treated patients.
dc.publisherBioMed Central
dc.relation.ispartofRenal Replacement Therapy
dc.subjectVascular Access
dc.subjectArteriovenous Fistula
dc.subjectMaturation
dc.subjectHaemodialysis
dc.subjectSuccess Of Avf
dc.titleDevelopment of prognostic model for fistula maturation in patients with advanced renal failure
dc.typearticle
dcterms.accessRightspublic
dc.description.facultysch_pod
dc.description.volume4
dc.identifier.doihttp://doi:10.1186/s41100-018-0153-z
dc.description.ispublishedpub
dc.description.eprintid5237
rioxxterms.typearticle
refterms.dateAccepted2018-02-06
refterms.dateFCA2018-03-07
refterms.dateFCD2018-03-07
qmu.authorCarline, Tom
qmu.authorSiddiqui, Muhammad A.
qmu.authorAshraff, Suhel
qmu.authorSantos, Derek
qmu.authorRush, Robert
dc.description.statuspub
dc.description.number1


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