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dc.contributor.authorWarnock, Mary
dc.contributor.authorMcBean, Douglas
dc.contributor.authorSuter, Andreas
dc.contributor.authorTan, Jen
dc.contributor.authorWhittaker, Patricia
dc.date.accessioned2018-06-29T21:33:00Z
dc.date.available2018-06-29T21:33:00Z
dc.date.issued2007-12
dc.identifierER780
dc.identifier.citationWarnock, M., McBean, D., Suter, A., Tan, J. & Whittaker, P. (2007) Effectiveness and safety of Devil's Claw tablets in patients with general rheumatic disorders, Phytotherapy Research, vol. 21, , pp. 1228-1233,
dc.identifier.issn0951418X
dc.identifier.urihttp://dx.doi.org/10.1002/ptr.2288
dc.identifier.urihttps://eresearch.qmu.ac.uk/handle/20.500.12289/780
dc.description.abstractArthritis and other rheumatic conditions (AORC) are the leading cause of disability, are associated with poor quality of life and incur considerable direct and indirect costs. It is considered that the instance of AORC will continue to increase. To assess the effectiveness, safety and tolerability of Harpagophytum (Bioforce) in the treatment of AORC, a single group open study of 8 weeks duration (259 patients) was performed in the United Kingdom. Effectiveness was assessed by numeric rating scales, the Western Ontario and McMasters Universities Osteoarthritis (WOMAC) Index and the Algofunctional Hand Osteoarthritis Index. Tolerance was measured by a numeric rating scale and safety by self-reporting, blood analysis and liver function tests. Quality of life was measured by SF-12 questionnaire. There were statistically significant (p < 0.0001) improvements in patient assessment of global pain, stiffness and function. There were also statistically significant reductions in mean pain scores for hand, wrist, elbow, shoulder, hip, knee and back pain. Quality of life measurements (SF-12) were significantly increased from baseline and 60% patients either reduced or stopped concomitant pain medication. Harpagophytum is an effective and well-tolerated serious treatment option for mild to moderate degenerative rheumatic disorders providing improved quality of life measure. Copyright 2007 John Wiley & Sons, Ltd.
dc.format.extent1228-1233
dc.relation.ispartofPhytotherapy Research
dc.subjectDevil's Claw
dc.subjectGeneral rheumatic disorders
dc.subjectHarpagophytum
dc.subjectJoint pain
dc.titleEffectiveness and safety of Devil's Claw tablets in patients with general rheumatic disorders
dc.typearticle
dcterms.accessRightsrestricted
dc.description.facultysch_die
dc.description.volume21
dc.identifier.doihttp://doi:10.1002/ptr.2288
dc.description.ispublishedpub
dc.description.eprintid780
rioxxterms.typearticle
qmu.authorMcBean, Douglas
qmu.authorWarnock, Mary
dc.description.statuspub
dc.description.number12


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