Browsing by Person "Nel, Carolina"

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Cryptococcal-related mortality despite fluconazole preemptive treatment in a cryptococcal antigen (CrAg) screen-and-treat programme
(Oxford University Press, 2019-06-08) Wake, Rachel M.; Govender, Nelesh P.; Omar, Tanvier; Nel, Carolina; Mazanderani, Ahmad Haeri; Karat, Aaron S.; Ismail, Nazir A.; Tiemessen, Caroline T.; Jarvis, Joseph N.; Harrison, Thomas S.
Background. Cryptococcal antigen (CrAg) screening and treatment with preemptive fluconazole reduces the incidence of clinically evident cryptococcal meningitis in individuals living with advanced human immunodeficiency virus (HIV) disease. However, mortality remains higher in CrAg-positive than in CrAg-negative patients with similar CD4+ T-lymphocyte counts.