The Benefits and Implications of an Eight Week Anabolic/Androgenic Steroid Intervention at a Supratherapeutic Dose When paired with Resistance Exercise In Older Adults

Abstract

Anabolic and androgenic steroids (AAS) have for quite some time been considered a taboo topic and one which has rarely been researched further since the Anabolic Steroid Act of 1990 deemed them to be a controlled substance. Since that time research within this area has slowed down dramatically and the potential benefits as well as implications are rarely discussed. Contrarily, stroke rehabilitation is an area for great interest and research. It is the aim of the researcher to deem the safety and research the potential benefits of a supratherapeutic dose (higher than would be used to treat a medical condition) of AAS administered to an elderly research participant. AAS are widely recognised by literature to be some of the safest drugs when used safely and correctly. They are also acknowledged to have positive effects on individual health and wellbeing however it is also clear there is risk for organ stress, particularly in relation to the cardiac system. Inorder to establish safety and effectiveness of the interventions for use with stroke survivors, we will assess the responses of age matched otherwise healthy individuals. This pilot study will recruit 20 healthy, male, older adults (65+) to participate in an 8-week AAS cycle paired with an 8 week resistance training program to assess physical function, mental and emotional wellbeing. Upon completion of the trial, the researcher shall conclude whether or not it can be deemed proof of concept to administer the drug in a follow up study, to those who have suffered from stroke, based on its safety and overall effectiveness.