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Kidney Beam - a cost-effective digital intervention to improve mental health.

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dc.contributor.authorGreenwood, Sharlene A.
dc.contributor.authorBriggs, Juliet
dc.contributor.authorWalklin, Christy
dc.contributor.authorMangahis, Emmanuel
dc.contributor.authorYoung, Hannah ML.
dc.contributor.authorCastle, Ellen M.
dc.contributor.authorBillany, Roseanne E.
dc.contributor.authorAsgari, Elham
dc.contributor.authorBhandari, Sunil
dc.contributor.authorBishop, Nicolette
dc.contributor.authorBramham, Kate
dc.contributor.authorBurton, James O.
dc.contributor.authorCampbell, Jackie
dc.contributor.authorChilcot, Joseph
dc.contributor.authorCooper, Nicola
dc.contributor.authorDeelchand, Vashist
dc.contributor.authorGraham-Brown, Matthew PM.
dc.contributor.authorHaggis, Lynda
dc.contributor.authorHamilton, Alexander
dc.contributor.authorJesky, Mark
dc.contributor.authorKalra, Philip A.
dc.contributor.authorKoufaki, Pelagia
dc.contributor.authorMcCafferty, Kieran
dc.contributor.authorNixon, Andrew C.
dc.contributor.authorNoble, Helen
dc.contributor.authorSaynor, Zoe L.
dc.contributor.authorTaal, Maarten W.
dc.contributor.authorTollitt, James
dc.contributor.authorWheeler, David C.
dc.contributor.authorWilkinson, Thomas J.
dc.contributor.authorWorboys, Hannah
dc.contributor.authorMacdonald, Jamie
dc.date.accessioned2024-09-09T13:10:27Z
dc.date.available2024-09-09T13:10:27Z
dc.date.issued2024-09-02
dc.date.updated2024-09-05T01:28:30Z
dc.descriptionFrom Elsevier via Jisc Publications Router
dc.descriptionHistory: accepted 2024-08-27, issued 2024-09-02
dc.descriptionAM replaced with VoR 2024-11-27
dc.description.abstractBackground There is inequity in provision of physical rehabilitation services for people living with chronic kidney disease (CKD). The Kidney BEAM trial evaluated the clinical value and cost effectiveness of a physical activity digital health intervention in CKD. Methods In a single-blind, 11 centre, randomised controlled trial, 340 adult participants with CKD were randomly assigned to either the Kidney BEAM physical activity digital health intervention or a waitlist control. This study assesses the difference in the Kidney Disease Quality of Life Short Form 1.3 Mental Component Summary (KDQoL-SF1.3 MCS) between intervention and control groups at 6 months, and cost-effectiveness of the intervention. Results At 6 months there was a significant difference in mean adjusted change in KDQoL MCS score between Kidney BEAM and waitlist control (intention-to-treat adjusted mean: 5.9 {95% confidence interval: 4.4 to 7.5} arbitrary units, p<0.0001), and a 93% and 98% chance of the intervention being cost-effective at a willingness to pay threshold of £20,000 and £30,000 per quality-adjusted life year gained. Conclusion The Kidney BEAM physical activity digital health intervention is a clinically valuable and cost-effective means to improve mental health related quality of life in people with CKD (trial registration no. NCT04872933).
dc.description.ispublishedpub
dc.description.number11
dc.description.statuspub
dc.description.volume9
dc.format.extent3204–3217
dc.identifierdoi: 10.1016/j.ekir.2024.08.030
dc.identifierhttps://eresearch.qmu.ac.uk/handle/20.500.12289/13846/13846
dc.identifier.citationGreenwood, S.A., Briggs, J., Walklin, C., Mangahis, E., Young, H.M.L., Castle, E.M., Billany, R.E., Asgari, E., Bhandari, S., Bishop, N., Bramham, K., Burton, J.O., Campbell, J., Chilcot, J., Cooper, N., Deelchand, V., Graham-Brown, M.P.M., Haggis, L., Hamilton, A., Jesky, M., Kalra, P.A., Koufaki, P., McCafferty, K., Nixon, A.C., Noble, H., Saynor, Z.L., Taal, M.W., Tollitt, J., Wheeler, D.C., Wilkinson, T.J., Worboys, H. and Macdonald, J. (2024) ‘Kidney beam-a cost-effective digital intervention to improve mental health’, Kidney International Reports, 9(11), pp. 3204–3217. Available at: https://doi.org/10.1016/j.ekir.2024.08.030.
dc.identifier.urihttps://eresearch.qmu.ac.uk/handle/20.500.12289/13846
dc.identifier.urihttps://doi.org/10.1016/j.ekir.2024.08.030
dc.publisherElsevier
dc.rightsLicence for AM version of this article starting on 2024-08-28: http://creativecommons.org/licenses/by/4.0/
dc.rightsThis is an open access article distributed under the terms of the Creative Commons CC-BY license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You are not required to obtain permission to reuse this article.
dc.rights.licenseCC BY 4.0 Attribution 4.0 International Deed
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.en
dc.sourceissn: 24680249
dc.titleKidney Beam - a cost-effective digital intervention to improve mental health.
dc.typearticle
dcterms.accessRightspublic
dcterms.dateAccepted2024-08-27
qmu.authorKoufaki, Pelagia
qmu.centreCentre for Health, Activity and Rehabilitation Research
refterms.dateAccepted2024-08-27
refterms.dateDeposit2024-09-09
refterms.depositExceptionpublishedGoldOA
refterms.versionVoR
rioxxterms.publicationdate2024-09-02

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