Dietetics, Nutrition and Biological Sciences
Permanent URI for this collectionhttps://eresearch.qmu.ac.uk/handle/20.500.12289/23
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Item Nutritional status of children and adolescents with cancer in Scotland: A prospective cohort study(Elsevier, 2019-05-17) Revuelta-Iniesta, Raquel; Paciarotti, Ilenia; Davidson, Isobel; McKenzie, Jane M.; Brougham, Mark F. H.; Wilson, David C.Background and aims Malnutrition (under and overnutrition) in paediatric cancer patients during and after treatment increases short and long-term side-effects; however, factors contributing to malnutrition and patterns of change in nutritional status are still unclear. The aims were to investigate the prevalence of malnutrition, patterns of change in nutritional status and factors contributing to malnutrition in Scottish paediatric cancer patients.Item A Randomised Double Blind Placebo Controlled Trial of a Nucleotide-Containing Supplement Nucell on Symptoms of Participants with the Common Cold - A Pilot Study(ECronicon, 2016-05-20) Davidson, Isobel; Fyfe, LornaObjectives: To ascertain whether a nucleotide containing nutritional supplement Nucell attenuates self-reported symptoms of the common cold. Design: A randomised controlled trial. Setting: A University. Participants: Participants with self-reported symptoms of the common cold but otherwise healthy individuals. Intervention: Nucell capsules containing a yeast-based nucleotide preparation or placebo were provided over a 28 day period. Outcome Measures: Subjective ratings of symptoms were recorded by self-administered questionnaires using a nine-point scale. Salivary IgA concentrations were analysed from samples collected during the first 7 days and then at days 14,21 and 28 of supplementation. Total and white blood cell counts were also measured throughout the intervention. Results: Thirty-six participants completed the study. Nineteen received Nucell and 17 received the placebo. The mean age of participants was similar (29.8 + 2.5 in Nucell group v 30.7 + 2.7 in control group) and the time participants had been suffering from cold-related symptoms was not significantly different in each treatment group (2.5 + 0.40 days in Nucell v 2.9 + 0.47 days in control group). Severity of self-reported symptoms was significantly attenuated in the Nucell treated group in the first week of supplementation for questions asked with respect to taste, painful sinuses and earache (p< 0.05). Supplementation with Nucell did not adversely affect total or differential white blood counts. Conclusion: These results suggest that Nucell supplementation administered as a treatment for cold-related symptoms may reduce the severity of specific symptoms particularly in the early infective phase. In conclusion, Nucell supplementation may provide subjective relief of some cold-related symptoms and may be of significant benefit administered as a treatment in participants where sinus pain, earache and diminished taste are common symptoms.Item Morphological and functional changes associated with a 12-week self-guided exercise programme of overweight adults: A pilot study(Cambridge University Press, 2012) Stewart, A. D.; Rolland, Catherine; Gryka-MacPhail, Anna; Smith, Sara; Jones, Jacklyn; Findlay, Sally; Davidson, IsobelItem Grip strength is associated with nutritional status and energy intake in healthy community living older adults(Cambridge University Press, 2010) Jones, Jacklyn; Baer, Gill; Davidson, IsobelItem The contribution of the dietitian and nutritionist to palliative medicine(Oxford University Press, 2015) Richardson, Rosemary A.; Davidson, Isobel; Cherny, Nathan; Currow, David; Fallon, Marie; Kaasa, Stein; Portenoy, RussellItem The investigation of the effects of food texture and energy density on appetite and food intakes at a single eating occasion in older adults: A pilot study(Cambridge University Press, 2011-01) Pritchard, S.; Bannerman, Elaine; Jones, Jacklyn; Davidson, IsobelItem Dietary intakes in geriatric orthopaedic rehabilitation patients: Need to look at food consumption not just provision(Elsevier, 2015-06-19) Bannerman, Elaine; Cantwell, Linda; Gaff, Lisa; Conroy, Ashiling; Davidson, Isobel; Jones, JacklynItem An investigation into food provision and consumption in an orthopaedic rehabilitation hospital in Scotland, UK(Cambridge University Press, 2011-01) Williams, L.; Jones, Jacklyn; Davidson, Isobel; Bannerman, ElaineItem A study of Fluid provision and consumption in a rehabilitation hospital in Scotland, UK(Cambridge University Press, 2011-01) Williams, L.; Jones, Jacklyn; Davidson, Isobel; Bannerman, ElaineItem 25-hydroxyvitamin D concentration in paediatric cancer patients from Scotland: A prospective cohort study(Cambridge University Press, 2016-12-15) Revuelta-Iniesta, Raquel; Paciarotti, Ilenia; Davidson, Isobel; McKenzie, Jane; Brand, Celia; Chin, Richard; Brougham, Mark FH; Wilson, D. C.Children with cancer are potentially at high risk of plasma 25-hydroxyvitamin D [25(OH)D] inadequacy and despite UK vitamin D supplementation guidelines their implementation remains inconsistent. Thus, we aimed to investigate 25(OH)D concentration and factors contributing to 25(OH)D inadequacy in paediatric cancer patients. A prospective cohort study of Scottish children aged <18 years, diagnosed with and treated for cancer (patients) between Aug 2010-Jan 2014 was performed, with control data from Scottish healthy children (controls). Clinical and nutritional data were collected at defined periods up to 24 months. 25(OH)D status was defined by the Royal College of Paediatrics and Child Health (2013); inadequacy [<50 nmol/L: deficiency (<25 nmol/L), insufficiency (25-50 nmol/L)], sufficiency (51-75 nmol/L), optimal (>75 nmol/L). Eighty-two patients [median(IQR) age 3.9(1.9-8.8); 56% males)] and 35 controls [median(IQR) age (6.2(4.8-9.1); 49% males] were recruited. 25(OH)D inadequacy was highly prevalent in the controls (63%; 22/35), and in the patients (64%; 42/65) at both baseline and during treatment (33-50%). Non-supplemented children had the highest prevalence of 25(OH)D inadequacy at every stage with 25(OH)D median(IQR) ranging from 32.0 (21.0-46.5) nmol/L to 45.0(28.0-64.5) nmol/L. Older age at baseline [R=-0.46; p<0.001], overnutrition (BMI ≥85th centile) at 3 months [p=0.005; RR=3.1] and not being supplemented at 6 months (p=0.04; RR=4.3) may have contributed to lower plasma 25(OH)D. Paediatric cancer patients are not at higher risk of 25(OH)D inadequacy than healthy children at diagnosis; however prevalence of 25(OH)D inadequacy is still high and non-supplemented children have a higher risk. Appropriate monitoring and therapeutic supplementation should be implemented.