Dietetics, Nutrition and Biological Sciences
Permanent URI for this collectionhttps://eresearch.qmu.ac.uk/handle/20.500.12289/23
Browse
2 results
Search Results
Item Effects of oat β-glucan consumption at breakfast on ad libitum eating, appetite, glycemia, insulinemia and GLP-1 concentrations in healthy subjects.(2018-06-18) Zaremba, Suzanne; Gow, Iain F.; Drummond, Sandra; McCluskey, Jane T.; Steinert, Robert E.There is evidence that oat β-glucan lowers appetite and ad libitum eating; however, not all studies are consistent, and the underpinning mechanisms are not entirely understood. We investigated the effects of 4 g high molecular weight (MW) oat β-glucan on ad libitum eating, subjective appetite, glycemia, insulinemia and plasma GLP-1 responses in 33 normal-weight subjects (22 female/11 male, mean age (y): 26.9 ± 1.0, BMI (kg/m ): 23.5 ± 0.4). The study followed a randomised double-blind, cross-over design with subjects fed two test breakfasts with and without oat β-glucan followed by an ad libitum test meal on two different days. Blood samples and ratings for subjective appetite were collected postprandially at regular time intervals. Oat β-glucan increased feelings of fullness (p = 0.048) and satiety (p = 0.034), but did not affect energy and amount eaten at the ad libitum test meal. There was a treatment by time interaction for plasma GLP-1, plasma insulin and blood glucose. GLP-1 was significantly reduced at 90 min (p = 0.021), blood glucose at 30 min (p = 0.008) and plasma insulin at 30 and 60 min (p = 0.002 and 0.017, respectively) following the oat β-glucan breakfast when compared with the control breakfast. Four grams of high MW oat β-glucan lowers appetite but not ad libitum eating and beneficially modulates postprandial glycaemia, it does however, not increase plasma GLP-1 secretion. [Abstract copyright: Copyright © 2018 Elsevier Ltd. All rights reserved.]Item The need to standardize ad libitum eating protocols in dietary fibre appetite research(Nature Publishing Group, 2016-12-21) Zaremba, Suzanne; Drummond, Sandra; Steinert, R. E.Since more than 1.9 billion adults worldwide are overweight, of which 600 million are obese,1 it is of vital importance to identify treatment strategies to help overweight and obese patients to lose weight and to improve long-term health. From a nutrition perspective, research has focussed on increasing the satiating power of the diet so that individuals feel full with fewer calories. A potentially effective class of functional foods, modulating appetite and food intake in such ways, is dietary fibre. However, although emerging evidence highlights the positive effects of dietary fibre on appetite and body weight, the methodological approaches are not always consistent and give rise to many uncertainties.