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    Effect of Oatmeal on Postprandial Vascular Compliance Following a High Fat Meal

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    eResearch%204327.pdf (270.8Kb)
    Date
    2016-02-12
    Author
    Devlin, N.
    McKenzie, Jane
    Gow, Iain F.
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    Citation
    Devlin, N., McKenzie, J. & Gow, I. (2016) Effect of Oatmeal on Postprandial Vascular Compliance Following a High Fat Meal, Journal of Clinical Nutrition and Dietetics, vol. 2, , pp. 4,
    Abstract
    Background and aim: Postprandial hyperlipidaemia has been associated with acute cardiovascular effects e.g. endothelial dysfunction and peripheral vasodilatation. Oats have known health benefits, and may reduce the transient, post-prandial endothelial dysfunction. The aim of this short study was to investigate if markers of endothelial function pulse wave velocity (PWV) and augmentation index corrected for heart rate (AIx@75) are affected by a meal with varying levels of saturated fat, with or without oatmeal. Methods and results: Fourteen subjects (aged between 22 and 51 years) were recruited. On their first visit, following baseline measurements of anthropometry, blood pressure (BP), heart rate (HR), PWV and AIx@75, they were given one of three meals (low fat, high fat, and high fat with 60g oatmeal) in a randomised order. Subjects returned three hours later for re-assessment of BP, PWV and AIx@75. Visits two and three followed the same protocol, but only BP, HR, PWV and AIx@75 were measured. There was a significant correlation between baseline PWV and systolic pressure (p<0.02), and AIx@75 and diastolic pressure (p<0.005). AIx@75 was positively related to BMI and waist circumference (p<0.01 and p<0.005 respectively). AIx@75 fell following the high fat meal (p<0.05), but not when oats were taken. Heart rate increased following the high fat meal with oats (p<0.05), but no differences were found between fasting and postprandial PWV after any of the meals. Conclusion: AIx@75 was correlated with BMI and waist circumference. The decrease in AIx@75 following the high fat meal requires further investigation, and AIx@75 is possibly a more sensitive marker of arterial compliance than PWV in a young healthy population.
    URI
    http://clinical-nutrition.imedpub.com/effect-of-oatmeal-on-postprandial-vascular-compliance-following-a-high-fat-meal.php?aid=8549
    URI
    https://eresearch.qmu.ac.uk/handle/20.500.12289/4327
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    • Dietetics, Nutrition and Biological Sciences

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