A study of wound healing in the E11.5 mouse embryo by light and electron microscopy
McCluskey, Jane T.
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McCluskey, J., Hopkinson-Woolley, J., Luke, B. & Martin, P. (1993) A study of wound healing in the E11.5 mouse embryo by light and electron microscopy, Tissue and Cell, vol. 25, , pp. 173-181,
In this paper we report our light and electron microscopic studies of the healing of a simple excisional lesion to the E11.5 mouse embryo hindlimb. The wounded living embryo is cultured in a roller bottle and under such conditions the lesion is completely re-covered with epithelium by 24 hr. We discuss how our studies of such a simple wound healing model may offer insight into the mechanisms of tissue repair generally.