Plant active components - a resource for antiparasitic agents?
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Date
2005-10Author
Anthony, Jean-Paul
Fyfe, Lorna
Smith, Huw
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Anthony, J., Fyfe, L. & Smith, H. (2005) Plant active components - a resource for antiparasitic agents? Trends in Parasitology, 21(10), pp. 462-468.
Abstract
Plant essential oils (and/or active components) can be used as alternatives or adjuncts to current antiparasitic therapies. Garlic oil has broad-spectrum activity against Trypanosoma, Plasmodium, Giardia and Leishmania, and Cochlospermum planchonii and Croton cajucara oils specifically inhibit Plasmodium falciparum and Leishmania amazonensis, respectively. Some plant oils have immunomodulatory effects that could modify host-parasite immunobiology, and the lipid solubility of plant oils might offer alternative, transcutaneous delivery routes. The emergence of parasites resistant to current chemotherapies highlights the importance of plant essential oils as novel antiparasitic agents. Paper adds to the growing body of evidence that children can acquire phonological systems before they are able to master the phonetic skills needed to convey the contrasts in that system