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    Baroreflex function, haemodynamic responses to an orthostatic challenge, and falls in haemodialysis patients [SP400] (Abstract)

    Date
    2018-05-18
    Author
    Zanotto, Tobia
    Koufaki, Pelagia
    Mercer, Tom
    van der Linden, Marietta
    Traynor, Jamie
    Petrie, Colin
    Price, Jonathan
    Oun, Hadi
    Shilliday, Ilona
    Metadata
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    Citation
    Zanotto, T., Koufaki, P., Mercer, T., van der Linden, M., Traynor, J., Petrie, C., Price, J., Oun, H. & Shilliday, I. (2018) Baroreflex function, haemodynamic responses to an orthostatic challenge, and falls in haemodialysis patients [SP400] (Abstract), Nephrology Dialysis Transplantation, 33 (Suppl_1), i482.
    Abstract
    Background: The prevalence of falls among Stage 5 chronic kidney disease (CKD-5) patients undergoing haemodialysis (HD) therapy ranges from 26.3% to 47%, and is considerably higher than in the general healthy population. In addition to traditional risk factors such as older age, frailty, comorbidity, and polypharmacy, these patients often present with dizziness and pre-syncopal events as a result of the combined effect of HD therapy and cardiovascular disease, which may contribute to an increased risk of falling. Particularly, it has been suggested that the dysregulation of blood pressure during orthostasis may play a role in the aetiology of falls in these patients. Purpose of the study: To compare the haemodynamic responses to a passive orthostatic challenge, as well as the baroreflex function, in HD patients with and without history of falls.
    Official URL
    https://doi.org/10.1093/ndt/gfy104
    URI
    https://eresearch.qmu.ac.uk/handle/20.500.12289/5380
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