Queen Margaret University logo
    • Login
    View Item 
    •   QMU Repositories
    • eResearch
    • School of Health Sciences
    • Dietetics, Nutrition and Biological Sciences
    • View Item
    •   QMU Repositories
    • eResearch
    • School of Health Sciences
    • Dietetics, Nutrition and Biological Sciences
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Effects of oat β-glucan consumption at breakfast on ad libitum eating, appetite, glycemia, insulinemia and GLP-1 concentrations in healthy subjects.

    View/Open
    Accepted Version (938.4Kb)
    Date
    2018-06-18
    Author
    Zaremba, Suzanne
    Gow, Iain F.
    Drummond, Sandra
    McCluskey, Jane T.
    Steinert, Robert E.
    Metadata
    Show full item record
    Citation
    Zaremba, S., Gow, I. F., Drummond, S., McCluskey, J. T. & Steinert, Robert E. (2018) Effects of oat β-glucan consumption at breakfast on ad libitum eating, appetite, glycemia, insulinemia and GLP-1 concentrations in healthy subjects. Appetite, 128, pp. 197-204.
    Abstract
    There is evidence that oat β-glucan lowers appetite and ad libitum eating; however, not all studies are consistent, and the underpinning mechanisms are not entirely understood. We investigated the effects of 4 g high molecular weight (MW) oat β-glucan on ad libitum eating, subjective appetite, glycemia, insulinemia and plasma GLP-1 responses in 33 normal-weight subjects (22 female/11 male, mean age (y): 26.9 ± 1.0, BMI (kg/m ): 23.5 ± 0.4). The study followed a randomised double-blind, cross-over design with subjects fed two test breakfasts with and without oat β-glucan followed by an ad libitum test meal on two different days. Blood samples and ratings for subjective appetite were collected postprandially at regular time intervals. Oat β-glucan increased feelings of fullness (p = 0.048) and satiety (p = 0.034), but did not affect energy and amount eaten at the ad libitum test meal. There was a treatment by time interaction for plasma GLP-1, plasma insulin and blood glucose. GLP-1 was significantly reduced at 90 min (p = 0.021), blood glucose at 30 min (p = 0.008) and plasma insulin at 30 and 60 min (p = 0.002 and 0.017, respectively) following the oat β-glucan breakfast when compared with the control breakfast. Four grams of high MW oat β-glucan lowers appetite but not ad libitum eating and beneficially modulates postprandial glycaemia, it does however, not increase plasma GLP-1 secretion. [Abstract copyright: Copyright © 2018 Elsevier Ltd. All rights reserved.]
    Official URL
    https://doi.org/10.1016/j.appet.2018.06.019
    URI
    https://eresearch.qmu.ac.uk/handle/20.500.12289/5412
    Collections
    • Dietetics, Nutrition and Biological Sciences

    Queen Margaret University: Research Repositories
    Accessibility Statement | Repository Policies | Contact Us | Send Feedback | HTML Sitemap

     

    Browse

    All QMU RepositoriesCommunities & CollectionsBy YearBy PersonBy TitleBy QMU AuthorBy Research CentreThis CollectionBy YearBy PersonBy TitleBy QMU AuthorBy Research Centre

    My Account

    LoginRegister

    Queen Margaret University: Research Repositories
    Accessibility Statement | Repository Policies | Contact Us | Send Feedback | HTML Sitemap