A study of wound healing in the E11.5 mouse embryo by light and electron microscopy
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Date
1993-04
Citation
McCluskey, J., Hopkinson-Woolley, J., Luke, B. and Martin, P. (1993) ‘A study of wound healing in the E11.5 mouse embryo by light and electron microscopy’, Tissue and Cell, 25(2), pp. 173–181. Available at: https://doi.org/10.1016/0040-8166(93)90017-F.
Abstract
In this paper we report our light and electron microscopic studies of the healing of a simple excisional lesion to the E11.5 mouse embryo hindlimb. The wounded living embryo is cultured in a roller bottle and under such conditions the lesion is completely re-covered with epithelium by 24 hr. We discuss how our studies of such a simple wound healing model may offer insight into the mechanisms of tissue repair generally.